
DraftKings NFL DFS Picks For Week 10 Main Slate: Ollie Gordon Rides Again
Adam Pfeifer breaks down the Week 10 NFL DFS main slate, where Ollie Gordon is set up for a significant workload against the struggling Colts.
The Week 10 NFL DFS slate offers plenty of value as we chase some high point totals, players returning from injuries and a few situations altered by the trade deadline.
Here are my top plays for the Week 10 DraftKings DFS main slate.
Quarterback
Bryce Young @ New Orleans Saints ($5,800)

Following consecutive down games, Bryce Young surprisingly bounced back against the Broncos last week, throwing for 276 yards, three touchdowns and one interception. Building momentum entering Week 10, Young gets a very fantasy-friendly road matchup with the Saints in a game that should feature plenty of possessions.
We love that.
Both the Panthers and Saints rank top 10 in pace of play this season, while Kellen Moore’s group is once again among the league leaders in no-huddle rate (14%). Carolina, meanwhile, continues to throw the ball all over the field, ranking third in the NFL in dropback rate over expected (4%) and overall dropback rate (66%). This NFC South showdown could be an absolute track meet with Young getting a strong matchup.
New Orleans is coughing up 18.3 fantasy points per game to opposing signal callers (12th-most), as well as the 10th-highest completion rate (65.5%). The key to Young succeeding is Carolina’s ability to slow down any pass rush, as the offensive line has been an issue for much of the season. New Orleans has Chase Young and Carl Granderson who can sack the quarterback, but overall the team is generating pressure at the league’s seventh-lowest rate. When not pressured this season, Young is averaging 8.1 YPA (9th) with 11 TDs to 3 INTs.
Others to consider:
- Josh Allen @ NYJ ($7,500)
- Brock Purdy @ DAL ($7,000)
RELATED: Fantasy Life's NFL Betting Game Model provides bettors with projected spreads, totals and projected win percentage for the home team to help bettors accurately handicap all Week 10 games.
Running Back
James Cook @ New York Jets ($7,400)

James Cook is coming off 31 carries against the Vikings, and while he’s unlikely to see that much work again, I do believe he’ll find a lot more room to run against the Jets. New York is coughing up the fifth-most rushing yards per game to opposing backfields this season (110.3), as well as the ninth-most fantasy points per game to opposing running backs. They’ve been especially vulnerable without defensive tackle T’Vondre Sweat in the middle of the defense, surrendering 4.5 YPC, seven rushing touchdowns and 1.5 YBC/ATT with him off the field this season.
Sweat was placed on injured reserve ahead of Week 8, and the Jets' explosive rush rate allowed has climbed to over 11% over the past two weeks. For reference, it was just 8.5% with Sweat active during Weeks 1-7. Cook is a solid road favorite and has found the end zone in each of his last seven games. This is a great spot for him to keep it going.
Ollie Gordon @ Indianapolis Colts ($5,800)

Since becoming Miami’s starting running back in Week 4, Ollie Gordon has logged 73% of the snaps (eighth in the league), 69% of the rush attempts (10th) and 82% of the inside-the-five carries (eighth). During that span, Gordon’s 17.4 carries per game are the ninth-most in the NFL, operating as fantasy’s RB21 on a PPG basis. Each week, you’d be tough to project many running backs with more carries than Gordon, and the only thing keeping him from flirting with low-end RB1 status has been consistent pass game usage.
Gordon isn’t suddenly going to become Jahmyr Gibbs or Christian McCaffrey, but we could see a slight bump in targets going forward. Kyle McCord is set to take over at quarterback following Malik Willis’ move to injured reserve, which could lead to more check-downs to the running backs. Willis is sporting just an 11.6% checkdown rate this season, which ranks 32nd among 33 qualified quarterbacks. McCord, meanwhile, heavily targeted RB LeQuint Allen during his time at Syracuse, so we could absolutely see more dump-offs to Gordon out of the backfield going forward.
A matchup with the Colts is one of the best a running back can ask for right now. Indianapolis has allowed five different running backs to rush for 100-plus yards this season, while coughing up the fourth-most fantasy points per game to opposing backfields. The Colts are stuffing just 17% of all runs at or behind the line of scrimmage, the second-lowest rate in football, while their 10.2% explosive rush rate allowed is ninth-worst.
Others to consider:
- Chuba Hubbard @ NO ($7,200)
- Bhayshul Tuten @ TEN ($6,600)
- Zach Charbonnet @ LV ($5,600)
Wide Receiver
Justin Jefferson @ Green Bay Packers ($6,800)

Captain Kirk is home.
Kirk Cousins was traded to the Vikings on Tuesday, reuniting him with Kevin O’Connell, the Minnesota organization and, most importantly, Justin Jefferson. It comes at a much-needed time, as the Vikings offense is coming off yet another disastrous showing. Carson Wentz’s 8-for-26, 81-yard, two-INT performance was the final straw.
Cousins is obviously familiar with Kevin O’Connell’s offense, running it as Minnesota’s starting quarterback from 2022-2023. During those seasons, Cousins posted strong numbers, ranking third in passing yards (275), fifth in passing touchdowns (1.9) and fourth in completions (25.6) per game. His arrival is exactly what Jefferson needs to return to top-five fantasy WR status.
Jefferson and Cousins developed an awesome rapport a few years ago. And Cousins has always been great at simply getting the football to his best pass-catchers. Just look at Brock Bowers this season, Kyle Pitts last season (with Drake London out) and, of course, Jefferson, who averaged 10.7 targets, 7.4 receptions, 108.1 receiving yards and 21.3 PPR PPG with Cousins under center from 2022-23. Jefferson gets a matchup with a Green Bay defense he scored two touchdowns against back in Week 1, a secondary that is also surrendering the sixth-most receiving yards per game to opposing WR1s this year (80.7). Overall, the Packers are also allowing the seventh-most fantasy points per game to opposing wideouts.
With Cousins back under center, Jefferson is an elite play, especially sub-$7,000 on DraftKings.
Deebo Samuel @ Dallas Cowboys ($5,500)

Deebo Samuel hasn’t played since Week 5 but appears to be in line to make his return this Sunday. It comes at an ideal time, as Samuel gets one of the best matchups in all of fantasy football, facing a vulnerable Cowboys defense allowing the fourth-most points per drive (2.46). We know this defense is going to give up points, but there is one key data point that really favors Samuel.
No team in the NFL is allowing more yards after the catch per reception on WR screens than the Dallas Cowboys (14.6), while also allowing one touchdown off the play type. Samuel, of course, is heavily utilized in the screen game, as 8.9% of his routes have been WR screens, a top-five rate in football. We’ll see how large of a role Keenan Allen will play with his new team, but with Mike Evans once again sidelined, Samuel should see plenty of targets, particularly schemed looks to get him the ball in space.
Others to consider:
- Chris Olave vs. CAR ($7,000)
- Parker Washington @ TEN ($6,200)
- KC Concepcion vs. HOU ($4,800)
Tight End
Tyler Warren vs. Miami Dolphins ($4,400)

Tyler Warren, meet Fresh Prince alone in the empty house meme.
With Josh Downs and Keenan Allen traded, as well as Alec Pierce still sidelined, Warren suddenly finds himself as the last man standing for the Colts. The volume has already been strong for Warren (7.5 targets per game), but now it’ll potentially climb even more. Since last season, Warren has been targeted on a whopping 34% of his routes with both Downs and Pierce off the field. Granted, it isn’t the largest of sample sizes, but it illustrates the type of volume we could potentially see from Warren going forward.
I’d love to see the Colts try to use Warren a bit more down the field the rest of the way, as his 2.9 yards before the catch per reception ranks fifth-lowest among all non-running backs in football. But if Warren wasn’t deployed down the field with Allen and Downs operating underneath, I doubt it happens with both players now gone. Still, the volume will be elite, and the matchup is great. Miami is allowing the fourth-most fantasy points (14.4) per game to opposing tight ends this season.
Others to consider:
- George Kittle @ DAL ($6,500)
- Tyler Higbee @ ARI ($4,200)
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